Chicken Infectious Anaemia

"Blue wing disease" of chickens (egg-type pullets). Focal skin lesion on the wing+sides of the thorax.

Marked atrophy of the thymus

Multifocal to coalescing petechial and ecchymotic hemorrhages scattered across the mucosal surface of the intestine, set against marked mucosal pallor consistent with severe anemia.

Hemorrhages in the mucosa of the distal part of the proventriculus - Pullet, 7 wks old

Hemorrhages of the distal part of the proventriculus mucosa - Pullet, 7 wks old

"Blue wing disease" - Broiler 13 days old 

Severe, bilateral necrohemorrhagic dermatitis and extensive subcutaneous hemorrhage with cyanosis and edema, predominantly involving the wings ('blue wing disease').

Blue wing disease" of chickens (egg-type pullets). Focal skin lesion on the wing.

Pale comb of 6 week old pullet due to severe anemia.

Severe anemia evidenced by thin, watery blood with delayed or impaired clot formation, pooling over the pale subcutaneous tissues and musculature.

The depletion of hemocytoblasts due to virus-induced apoptosis leads to a drastic decrease in circulating erythrocytes, thrombocytes, and granulocytes. This hematological failure results in the characteristic clinical signs: extremely watery, thin blood, severe generalized anemia, and hemorrhages.

Severe gastrointestinal bleeding - Pullet 6 weeks-old