Narasin

Narasin

Description:

Narasin belongs to the polyether monocarboxylic acid class of ionophores.

 

Origin:

Fermentation product of Streptomyces aureofaciens.

 

Mode of Action:

The biological activity of narasin is based on its ability to form lipid soluble and dynamically reversible complexes with cations, preferably monovalent cations such as alkaline K+, Na+ and Rb+: Narasin functions as a carrier of these ions, mediating an electrically neutral exchangediffusion type of ion transport across the membranes. The resultant changes in transmembrane ion gradients and electrical potentials produce critical effects on cellular function and  metabolism of coccidia. Narasin is effective against sporozoites and early and late asexual stages of coccidia in broilers caused by Eimeria acervulina, E. brunetti, E. maxima, E. mivati, E. necatrix and E. tenella. Narasin also is used for prevention of necrotic enteritis in broiler chicken.

 

Dosage:

60-80 mg of active substance/kg of complete feed

 

Toxicity:

 

 

Drug combinations: