Infectious Diseases 2022

Infectious Diseases 2022

Why turkeys are highly susceptible to HPAI?

https://doi.org/10.1016/j.virusres.2022.198771 21 April, 2022

Turkeys, the third major poultry species in the world, are known to show broad susceptibility to various avian influenza viruses (AIVs).
In Europe and North America, where turkey consumption is popular, outbreaks of high and low pathogenicity avian influenza in turkeys have been frequently documented.  To elucidate the molecular basis of the broad susceptibility of turkeys to duck and chicken AIVs, a new study characterized various receptors for AIVs on their tissues.
The experimental infection of turkeys demonstrated that turkeys possess diverse Siaα2-3Gal glycans that facilitate their dual susceptibility to avian influenza viruses isolated from ducks and chickens.
The study also suggested the potential roles of turkeys in interspecies transmission of AIVs from ducks to chickens.