Infectious Diseases 2021

Infectious Diseases 2021

Gross pathology associated with HPAI H5N8 and H5N1

Lean et al. (2021) Vet Rec. e731. 30 July, 2021

In a study published in Veterinary Record, researchers described the pathology among poultry species naturally infected with HPAIV between October 2020 and April 2021, that have occurred in the United Kingdom. On gross examination, pancreatic necrosis was easily identified and most commonly observed in galliformes infected with both subtypes of HPAIV (H5N8 and H5N1) but rarely in anseriformes. In addition, splenic necrosis was also frequently observed in chickens and turkeys infected with HPAIV H5N8. Other less common lesions included cardiac petechiae, serosal haemorrhages and ascites in a variety of species.
Given the widespread dissemination of HPAIV infection in susceptible avian species during autumn/winter 2020–2021, these data, when evaluated along with clinical information, is a valuable first step for both veterinarians and field services to evaluate gross pathology at post-mortem to support the diagnosis of HPAIV infection.