Infectious Diseases 2020

Infectious Diseases 2020

EFSA: Antimicrobial resistance in the EU

6 March, 2020

Salmonella and Campylobacter are becoming increasingly resistant to ciprofloxacin, one of the antibiotics of choice for treating infections caused by these bacteria. The conclusion is part of the latest report on antimicrobial resistance in zoonoses released by the European Centre for Disease Prevention and Control (ECDC) and the European Food Safety Authority (EFSA), which also presents some positive trends in the animal sector.
The latest data from humans, animals and food show that a large proportion of Salmonella bacteria are multidrug-resistant (resistant to three or more antimicrobials). In humans, resistance to ciprofloxacin is common, particularly in certain types of Salmonella, and resistance to high concentrations of ciprofloxacin increased overall from 1.7% (2016) to 4.6% (2018).
For Campylobacter, 16 out of 19 countries report very high or extremely high percentages of ciprofloxacin resistance. High proportions of resistance to ciprofloxacin are also reported in Salmonella and E. coli bacteria from poultry. Ciprofloxacin is categorised as critically important for use in humans. Combined resistance - simultaneous resistance to two critically important antimicrobials - to fluoroquinolones and third generation cephalosporines in Salmonella and to fluoroquinolones and macrolides in Campylobacter remains low.
For 2018, the report lists sporadic cases of human Salmonella infection with resistance to carbapenems, a last-line antimicrobial. Finding carbapenem resistance in foodborne bacteria in the EU is a concern.
Regarding last-line antimicrobials, resistance to colistin was not common in Salmonella and E. coli, and carbapenemase-producing E. coli were not detected in broilers, turkeys and broiler meat. The positive findings in food-producing animals are encouraging because they are a sign of improvement.
In humans, the decline in resistance to ampicillin and to tetracyclines in Salmonella Typhimurium in many countries is another encouraging trend observed in 2013-2018.

Related Links
Link The report