Infectious Diseases 2019

Infectious Diseases 2019

The cause of wooden breast syndrome

Scientific Reports - 2019 24 November, 2019

University of Delaware researchers have discovered that lipoprotein lipase, an enzyme crucial for fat metabolism, may be contributing to wooden breast (WB) syndrome in broiler chickens. The researchers have identified gene expression irregularities at the onset of wooden breast syndrome that suggest the disease is a metabolic disorder characterized by abnormal fat accumulation in the breast muscle tissue.The expression of lipoprotein lipase was higher in chickens affected with wooden breast syndrome, leading more fat to accumulate in the chicken's pectoral (or breast) muscles. Lipoprotein lipase serves as a "metabolic gatekeeper" that determines how much fat is allowed inside a given tissue.
This study confirms the existence of slow myofiber-phenotype and provides mechanistic insights into increased lipid uptake and metabolism in WB disease process.