Robenidine

Robenidine

Description:

A guanidine derivative.

 

Dosage:

33 ppm

 

Stage of the life cycle affected by the drug

Arrests the development of the first-generation schizonts of E. tenella by preventing the formation of merozoites. An additional effect on gametogeny has been identified.

 

Pharmacokinetics: It is absorbed to a limited extent and excreted rapidly.
Unchanged robenidine is the major
compound excreted by chicken and turkey
Unchanged robenidine is the majorcompound excreted by chicken and turkey. In chickens, it is not completely absorbed from the GI tract; the absorbed portion is well distributed to tissues and extensively metabolized. Excretion occurs over several days following oral administration.
 
Toxicity:

Chicken LD50 450 mg/kg.

 

Precaution:

Unpleasant taste to broiler meat if not withdrawn before slaughter. The taste is also imparted to eggs of layers when fed at 66 ppm.
 
Residues: