Infectious Diseases 2017

Infectious Diseases 2017

MS vaccine could facilitate replication of avian influenza viruses

Poultry Science (2017) 96:3086–3095 4 September, 2017

A recent study published in Poultry Science revealed that Mycoplasma synoviae (MS) vaccine [MS vaccine used was Vaxsafe R MS (Bioproperties Pty Ltd)], could facilitate replication of avian influenza viruses and thus avian influenza virus infections can be worse after MS vaccination in layers, especially in AIV-endemic areas.
The presented data demonstrate that H9N2 AIV caused obvious clinical signs, induced significant reduction of body weights, antibody titer, cytokine expression and increased virus shedding in buccal and cloacal swabs in layers previously vaccinated against MS. MS vaccine enhanced pathogenesis of AI infection significantly and can act as a complicating factor during avian influenza infections in layers.