Infectious Diseases 2017

Infectious Diseases 2017

A suspected person‑to‑person transmission of avian influenza A (H7N9)

Chin Med J (2017) May 20;130(10):1255-1256 13 May, 2017

Since throat swab specimens obtained from three adult Chinese patients were confirmed as an avian‑origin influenza A (H7N9) virus by local Centers for Disease Control and Prevention (CDC) in China in 2013, many confirmed cases have been reported in Mainland of China. Although family and hospital clusters with confirmed or suspected avian H7N9 virus infection were previously reported and person‑to‑person transmission was put forward, human infection of H7N9 appears to be associated with exposure to infected live poultry or contaminated environments and no clear evidence has proved that it could transmit from person to person. Now, a group of chinese researchers report a case confirmed with H7N9 after intimately contact with his H7N9 ward mate, it may be the first case infected between ward mates in a ward. The index case patient 66‑year‑old male with hypertension and type II diabetes for more than 10 years, had visited a live‑poultry market (LPM) to buy food every day within 10 days before his illness onset and had no direct contact with live poultry in the market. 
Case 2 (index case’s ward mate), a 62‑year‑old male with no underlying disease, The second case in this report had physical contact with the index case when assisting the index case to the bathroom (it lasted for 10 min) and had no history of exposure to live poultry or LPMs before the illness onset. There were a lot of family members in the ward, but he was the only one who was in close contact with the index case, and he was the only one confirmed H7N9 besides the index case. To the best of our knowledge, the case indicates that it is human‑to‑human transmission happened in a ward with detailed epidemiological, clinical, virological data, and genome analyses of two collected H7N9 virus.


See: Person-to-person transmission of H5N1