Can a live MS vaccine reduce M. synoviae shedding?
Voluntary M. synoviae control and eradication programmes have been performed in some countries like the USA and the UK. Awareness of the increasing importance of M. synoviae prompted the Dutch poultry industry to implement a mandatory control and eradication programme for M. synoviae for all poultry categories except broilers. This programme, which was started in January 2013, is based on the successful control and eradication programme of Mycoplasma gallisepticum. Although M. synoviae vaccination could serve as an additional control measure by reducing for instance the infection pressure at infected multiple-age layer farms.
The implementation of compulsory vaccination in a control and eradication programme should only be made if two conditions are met:
1. It is shown that vaccination reduces the shedding and/or horizontal transmission of field M. synoviae.
2. Vaccinated flocks can still be monitored adequately despite the fact that they may seroconvert due to vaccination
Dutch researchers from GD – Animal Health, Deventer and the National Institute for Public Health and the Environment, Ministry of Health were able to demonstrate that vaccination with MS-H reduces the shedding and horizontal transmission of a field M. synoviae challenge strain.